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À¯¸Áº¥Ã³±â¾÷ PK/PD M&S(Modeling & Simulation) °æ·ÂÀÚ(5³âÀÌ»ó)¸ðÁý
Senior Scientist
Summary Description
This position participates as a member of the pharmacology team and is responsible for developing and executing PK-PD modeling and simulation (M&S) strategies in a collaborative environment with colleagues in preclinical and clinical pharmacology. This individual will apply state of the M&S methodologies to support the relationship PK and PD, FIH and middle stage clinical dose selection.
Key Responsibilities
Develop/apply state of the art PK-PD modelling techniques to guide advancement of drug candidates across development phases (preclinical through early clinical development).
Initiate and monitor outsourced M&S activities as required.
Actively participate as PK/PD lead with project teams.
Contribute to regulatory documents (e.g. IND) and attend meetings with regulators as required.
Experience & Education
PhD, PharmD in Pharmaceutical sciences, Pharmacology, Toxicology or related discipline.
At least 5 years of hands-on experience with development and application of M&S in a drug-development environment.
Expertise in a specific therapeutic area and ability to demonstrate successful application of M&S tools in that area.
Expert user of NONMEM, Phoenix-NLME, R/S-Plus or related software with requisite programming skills.
Demonstrated skills in development of novel modeling approaches that incorporate factors such as receptor affinity, binding kinetics, and diurnal flux in response.
Hands-on experience with PBPK model development and implementation is a plus.
Hands-on experience with PK-PD modeling strategies to guide advancement of drug candidates from discovery through early clinical development is a plus.
Excellent written/oral communication skills in English.
Familiarity with regulatory guidance/expectations applicable to M&S.
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1. À̷¼ Á¦Ãâó: À̸ÞÀÏ npc@nowpharm.co.kr
2. À̷¼´Â ±âº»ÀÌ·Â + °æ·Â±â¼ú¼ + ÀÚ±â¼Ò°³¼¸¦ ÇϳªÀÇ ÆÄÀÏ·Î ¸¸µé¾î ÁֽʽÿÀ.
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1) ¿î¿µÃÑ°ý ÃÖ³«¿ì´ëÇ¥ 010-2369-4316
2) °ü¸®Á÷¿ø ±èÁ¾¼®ºÎ»çÀå 010-3736-0844
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9) ¿µ¾÷,¸¶ÄÉÆà Á÷¿ø ÀÓ¼¼Á¾ ÀÌ»ç 010-4459-7980
10) ÇØ¿Ü»ç¾÷Á÷¿ø ÀüµÎ¸®½ÇÀå 010-2677-3820
11) ±âŸ¹®ÀÇ 02-555-5425//»ó¼¼±¸Àγ»¿ë
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